Cthrc1 cancer

WebJ Cancer 2016; 7(15):2213-2220. doi:10.7150/jca.16539 This issue Cite. Review. Multidimensional Roles of Collagen Triple Helix Repeat Containing 1 (CTHRC1) in Malignant Cancers . Neng Jiang 1*, … WebMar 1, 2024 · Metastasis is the main cause of gastric cancer (GC) related death and the underlying mechanisms still remain unclear. Collagen triple helix repeat containing 1 (CTHRC1) protein is known to be involved in tissue remodeling processes and closely associated with carcinogenesis and metastasis in solid tumors, but the functional role of …

CTHRC1 May Serve As A Prognostic Biomarker For Hepatocellular …

WebApr 10, 2024 · The strong invasive and metastatic nature of non-small cell lung cancer (NSCLC) leads to poor prognosis. Collagen triple helix repeat containing 1 (CTHRC1) is involved in cell migration, motility and invasion. The object of this study is to investigate the involvement of CTHRC1 in NSCLC invasion and metastasis. A proteomic analysis was … WebSep 23, 2024 · CTHRC1 may affect the occurrence and development of tumors by participating in the process of cell proliferation and migration, synthesis of type I collagen, and repair of damage to blood vessels in colorectal cancer, pancreatic cancer, HCC, etc. 6–9 CTHRC1 plays an important role in the pathogenesis of systemic lupus … the personal touch flandreau sd https://marinercontainer.com

Pan-cancer analysis combined with experiments predicts …

WebMar 30, 2012 · The gene, collagen triple helix repeat containing 1 (CTHRC1), has been reported to increase in several kinds of human solid cancers and is associated with tumor invasion and metastasis.To date, the expression and function of CTHRC1 in gastric cancer (GC) have not been reported. WebSep 28, 2024 · CTHRC1, collagen triple helix repeat containing-1; CAF, cancer-associated fibroblast; CM, conditioned media. CAFs promote EMT alterations in BC cells by secreting CTHRC1 EMT is a recognized biological process that plays a key role in tumor metastasis, and is characterized by the loss of epithelial markers (such as E-cadherin) … WebNov 14, 2024 · Although recent researches have reported that CTHRC1 upregulation in breast cancer promoting cell proliferation, invasion and migration could be through activating GSK-3β/β-catenin signaling, Citation 41 the exact mechanisms of CTHRC1 involvement in breast cancer remains unclear. Therefore, high expression of CTHRC1 … sichuan literature and art publishing house

TGFβ and the Tumor Microenvironment in Colorectal Cancer

Category:Frontiers Application Potential of CTHRC1 as a Diagnostic and ...

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Cthrc1 cancer

The Role of CTHRC1 in Regulation of Multiple Signaling and

WebJun 23, 2024 · Collagen triple helix repeat containing 1 (CTHRC1) has been found to be upregulated in ESCC. However, its role in tumourigenesis and progression of ESCC … WebOct 26, 2024 · The pan-cancer analysis showed that CTHRC1 was overexpressed in most tumors, and a significant correlation was observed between CTHRC1 expression and the …

Cthrc1 cancer

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WebOct 26, 2024 · The function of collagen triple helix repeat containing 1 (CTHRC1) as an oncogene has been reported in a growing number of publications. Bioinformatics methods represent a beneficial approach to examine the mechanism and function of the CTHRC1 gene in the disease process of cancers from a pan-cancer perspective. In this study, …

WebThis study aimed to investigate the prognostic value of CTHRC1, and further explore its association with immune infiltration in breast cancer. Javascript is currently disabled in … WebMar 20, 2024 · CTHRC1 is widely upregulated in several solid tumors, including melanoma, gastrointestinal cancer, breast cancer, thyroid cancer, liver cancer, and pancreatic …

WebMar 1, 2024 · Collagen triple helix repeat containing 1 (CTHRC1) is a glycosylated protein secreted during tissue repair, which reduces collagen matrix deposition and promotes cell migration. ... Studies have shown that CTHRC1 promotes colorectal cancer metastasis by inducing the Wnt/PCP signal transduction (Yang et al., 2015). In … WebCTHRC1 has a role in pancreatic cancer progression and metastasis by regulating migration and adhesion activities of cancer cells. PMID: 23222813; Data indicate that the upregulated expression of collagen triple helix repeat containing 1 (CTHRC1) in gastric carcinogenesis contributes to tumor cell invasion and metastasis.

WebOct 22, 2024 · The association of CTHRC1 with tumor progression is demonstrated in various human cancers, including hepatocellular carcinoma, gastric cancer, pancreatic cancer, GIST and colorectal cancer (1-3).In a meta-analysis done by Wang et al., the results revealed correlation of CTHRC1 expression with TNM stage in gastric cancer, …

WebMar 1, 2024 · Collagen triple helix repeat containing 1 (CTHRC1) is a glycosylated protein secreted during tissue repair, which reduces collagen matrix deposition and … the personal tax account hmrcWebOct 6, 2024 · In the current study, we comprehensively analyzed CTHRC1 in distinct human cancer subtypes for the first time and find more closely CTHRC1-associated cancer … sichuan machinery imp. \u0026 exp. corpWebFeb 22, 2007 · We originally identified collagen triple helix repeat containing-1 (Cthrc1) in a screen for differentially expressed genes in normal versus balloon-injured arteries. 1 In the vasculature, Cthrc1 expression is limited to injured tissue, where it is induced abundantly in adventitial fibroblasts and neointimal smooth muscle cells (SMCs). … the personal touch cateringWebNov 14, 2024 · The high expression was confirmed by detecting the relative RNA expression of CTHRC1 in paired breast cancer and nontumor samples. The CTHRC1 transcriptional … the personal shopperWebFeb 15, 2024 · In CRC, the deletion of SMAD4 in cancer cells resulted in a decrease in S100A8+ monocytes in the tumor microenvironment . Furthermore, the release of Collagen Triple Helix Repeat Containing 1 (CTHRC1) by CRC cells induced M2 polarization of TAMs through TGFβ signaling and further promoted hepatic metastasis in mouse models … sichuan longda livestock technology co. ltdWebCollagen triple helix repeat containing 1 is a protein that in humans is encoded by the CTHRC1 gene. Function. This locus encodes a protein that may play a role in the cellular response to arterial injury through involvement in vascular remodeling. Mutations at this locus have been associated with Barrett's esophagus and esophageal adenocarcinoma. sichuan lvzhijian lemon industry co. ltdWebMar 1, 2024 · Collagen triple helix repeat containing 1 (CTHRC1) protein is known to be involved in tissue remodeling processes and closely associated with carcinogenesis and … sichuan maccura biotechnology